Welcome to Professor Ashraf Brik’s laboratory at the Schulich Faculty of Chemistry in the Technion-Israel Institute of Technology.
Our research group is developing novel synthetic approaches to chemically synthesize homogenous posttranslationally modified proteins, such as ubiquitinated and phosphorylated proteins, for structural, biochemical, biophysical and functional analyses.
In addition, we are developing novel modulators based on small molecules, peptides and peptidomimetics for various enzymes (e.g. deubiquitinases) to study their function and inhibition and contribute to human health. Research in the Brik Lab is funded by several international and local funding agencies such as the Israel Science Foundation (ISF), the US-Israel Binational Science Foundation (BSF) and German-Israel Foundation (GIF).